Early Profound Secondary Autoimmune Thrombocytopenia Induced by Clopidogrel in a Patient with a Coronary Artery Stent
نویسندگان
چکیده
Clopidogrel in combination with aspirin is commonly used for the prevention of thrombosis in patients with coronary artery stents [1]. moreover, since being introduced clopidogrel has proven to be very safe, tolerable, and efficacious [2]. Indications for clopidogrel use are expanding, and include reduction of such cardiovascular events as myocardial infarction and stroke in appropriate patients. As the use of clopidogrel increases, uncommon side effects are encountered more frequently [3]. Autoimmune thrombocytopenia is an extremely rare adverse effect of clopidogrel therapy [4]. We report a case of autoimmune thrombocytopenia related to standard clopidogrel treatment in a patient 2 days after coronary stenting.
منابع مشابه
Drug-induced cholestasis: case report
Background: Clopidogrel is an effective anti-platelet drug that is commonly prescribed for patients with atherosclerotic coronary and peripheral vascular diseases, especially after angioplasty and coronary artery bypass graft surgery. Even though this drug seems safe, there are case reports of important side effects with its use. Case Presentation: The patient was 67 years old male admitted wi...
متن کاملClopidogrel-Associated Thrombotic Thrombocytopenic Purpura following Endovascular Treatment of Spontaneous Carotid Artery Dissection
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening multisystem disease secondary to platelet aggregation. We present a patient who developed profound thrombocytopenia and anemia 8 days following initiation of therapy with clopidogrel after stent placement for carotid artery dissection. She did not have a disintegrin and metalloproteinase with thrombospondin domain 13 (ADAMTS 13) de...
متن کاملIn-hospital and late outcomes after coronary stenting in patient with unstable angina and myelodysplastic syndrome.
Sixty-one-year-old male patient with diagnosis of myelodysplastic syndrome and unstable angina was submitted to coronary angiography and implant of stent. His Blood cell count revealed 40,000 platelets/mm3. Coronary angiography with previous platelet transfusion showed obstruction of 80% of the right coronary artery (RCA). Following the administration of clopidogrel, the patient was submitted t...
متن کاملAcute profound thrombocytopenia following angioplasty: the dilemma in the management and a review of the literature.
Abciximab, heparin, and clopidogrel are often used together in the setting of coronary syndromes. These drugs are associated with thrombocytopenia and it is important to quickly discriminate the cause of this complication as it has implications for the management of thrombocytopenia and the coronary syndrome. This case highlights some of the dilemmas that may arise as no test can definitively i...
متن کاملManagement of Catheter Induced Upper Limb Suppurative Thrombophlebitis in a Patient after Coronary Artery Bypass Graft Surgery: a Case Report
Introduction: One of the important complications of peripheral venous catheters is suppurative thrombophlebitis that would be life threatening without treatment. In this report, we introduce a patient who developed purulent thrombophlebitis due to venous catheter in the upper limb after coronary artery bypass graft surgery. Multiple abscess formation was developed on her upper limb after the th...
متن کامل